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Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential
Normal stem cells reside in functional niches critical for self-renewal and maintenance. Neural and hematopoietic stem cell niches, in particular, are characterized by restricted availability of oxygen and the resulting regulation by hypoxia-inducible factors (HIFs). Glioblastoma multiforme (GBM) is...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229666/ https://ncbi.nlm.nih.gov/pubmed/21836617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.109 |
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