Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential

Normal stem cells reside in functional niches critical for self-renewal and maintenance. Neural and hematopoietic stem cell niches, in particular, are characterized by restricted availability of oxygen and the resulting regulation by hypoxia-inducible factors (HIFs). Glioblastoma multiforme (GBM) is...

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Main Authors: Heddleston, J M, Wu, Q, Rivera, M, Minhas, S, Lathia, J D, Sloan, A E, Iliopoulos, O, Hjelmeland, A B, Rich, J N
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229666/
https://ncbi.nlm.nih.gov/pubmed/21836617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.109
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