Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

Glioblastomas are lethal cancers characterized by florid angiogenesis promoted in part by glioma stem cells (GSCs). As hypoxia regulates angiogenesis, we examined hypoxic responses in GSCs. We now demonstrate that hypoxia-inducible factor HIF2α and multiple HIF-regulated genes are preferentially exp...

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Main Authors: Li, Zhizhong, Bao, Shideng, Wu, Qiulian, Wang, Hui, Eyler, Christine, Sathornsumetee, Sith, Shi, Qing, Cao, Yiting, Lathia, Justin, McLendon, Roger E., Hjelmeland, Anita B., Rich, Jeremy N.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693960/
https://ncbi.nlm.nih.gov/pubmed/19477429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.03.018
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