Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

Glioblastomas are lethal cancers characterized by florid angiogenesis promoted in part by glioma stem cells (GSCs). As hypoxia regulates angiogenesis, we examined hypoxic responses in GSCs. We now demonstrate that hypoxia-inducible factor HIF2α and multiple HIF-regulated genes are preferentially exp...

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Detalhes bibliográficos
Main Authors: Li, Zhizhong, Bao, Shideng, Wu, Qiulian, Wang, Hui, Eyler, Christine, Sathornsumetee, Sith, Shi, Qing, Cao, Yiting, Lathia, Justin, McLendon, Roger E., Hjelmeland, Anita B., Rich, Jeremy N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693960/
https://ncbi.nlm.nih.gov/pubmed/19477429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.03.018
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