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Targeting Cancer Stem Cells through L1CAM Suppresses Glioma Growth

Malignant gliomas are extremely lethal cancers that display striking cellular heterogeneity. A highly tumorigenic glioma tumor subpopulation, termed cancer stem cells or tumor-initiating cells, promotes therapeutic resistance and tumor angiogenesis. Therefore, targeting cancer stem cells may improve...

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Autores principales: Bao, Shideng, Wu, Qiulian, Li, Zhizhong, Sathornsumetee, Sith, Wang, Hui, McLendon, Roger E., Hjelmeland, Anita B., Rich, Jeremy N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739001/
https://ncbi.nlm.nih.gov/pubmed/18676824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1079
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