c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

BACKGROUND: Malignant gliomas rank among the most lethal cancers. Gliomas display a striking cellular heterogeneity with a hierarchy of differentiation states. Recent studies support the existence of cancer stem cells in gliomas that are functionally defined by their capacity for extensive self-rene...

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Main Authors: Wang, Jialiang, Wang, Hui, Li, Zhizhong, Wu, Qiulian, Lathia, Justin D., McLendon, Roger E., Hjelmeland, Anita B., Rich, Jeremy N.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582454/
https://ncbi.nlm.nih.gov/pubmed/19020659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003769
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