Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth

Glioblastomas are deadly cancers that display a functional cellular hierarchy maintained by self-renewing glioblastoma stem cells (GSCs). GSCs are regulated by molecular pathways distinct from the bulk tumor that may be useful therapeutic targets. We determined that A20 (TNFAIP3), a regulator of cel...

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Detalhes bibliográficos
Main Authors: Hjelmeland, Anita B., Wu, Qiulian, Wickman, Sarah, Eyler, Christine, Heddleston, John, Shi, Qing, Lathia, Justin D., MacSwords, Jennifer, Lee, Jeongwu, McLendon, Roger E., Rich, Jeremy N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826371/
https://ncbi.nlm.nih.gov/pubmed/20186265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000319
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