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Hypoxia inducible factors in cancer stem cells

Oxygen is an essential regulator of cellular metabolism, survival, and proliferation. Cellular responses to oxygen levels are monitored, in part, by the transcriptional activity of the hypoxia inducible factors (HIFs). Under hypoxia, HIFs regulate a variety of pro-angiogenic and pro-glycolysis pathw...

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Détails bibliographiques
Auteurs principaux: Heddleston, J M, Li, Z, Lathia, J D, Bao, S, Hjelmeland, A B, Rich, J N
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833246/
https://ncbi.nlm.nih.gov/pubmed/20104230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605551
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