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Hypoxia-Inducible Factors in Cancer Stem Cells and Inflammation
Hypoxia-inducible factors (HIF) mediate metabolic switch in cells in hypoxic environments, including those in both normal and malignant tissues with limited supplies of oxygen. Paradoxically, recent studies have shown that cancer stem cells and activated immune effector cells exhibit high HIF activi...
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Publicado no: | Trends Pharmacol Sci |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461458/ https://ncbi.nlm.nih.gov/pubmed/25857287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.03.003 |
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