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Hypoxia-Inducible Factors in Cancer Stem Cells and Inflammation
Hypoxia-inducible factors (HIF) mediate metabolic switch in cells in hypoxic environments, including those in both normal and malignant tissues with limited supplies of oxygen. Paradoxically, recent studies have shown that cancer stem cells and activated immune effector cells exhibit high HIF activi...
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| Published in: | Trends Pharmacol Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461458/ https://ncbi.nlm.nih.gov/pubmed/25857287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.03.003 |
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