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Hypoxia-Inducible Factors in Cancer Stem Cells and Inflammation

Hypoxia-inducible factors (HIF) mediate metabolic switch in cells in hypoxic environments, including those in both normal and malignant tissues with limited supplies of oxygen. Paradoxically, recent studies have shown that cancer stem cells and activated immune effector cells exhibit high HIF activi...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: Peng, Gong, Liu, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461458/
https://ncbi.nlm.nih.gov/pubmed/25857287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.03.003
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