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Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells

Triple negative breast cancers (TNBCs) are defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 expression, and are treated with cytotoxic chemotherapy such as paclitaxel or gemcitabine, with a durable response rate of less than 20%....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Samanta, Debangshu, Gilkes, Daniele M., Chaturvedi, Pallavi, Xiang, Lisha, Semenza, Gregg L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273385/
https://ncbi.nlm.nih.gov/pubmed/25453096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421438111
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