Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

Extracellular vesicles such as exosomes and microvesicles (MVs) are shed by cancer cells, are detected in the plasma of cancer patients, and promote cancer progression, but the molecular mechanisms regulating their production are not well understood. Intratumoral hypoxia is common in advanced breast...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Ting, Gilkes, Daniele M., Takano, Naoharu, Xiang, Lisha, Luo, Weibo, Bishop, Corey J., Chaturvedi, Pallavi, Green, Jordan J., Semenza, Gregg L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128139/
https://ncbi.nlm.nih.gov/pubmed/24938788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410041111
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