Regulation of CAR and PXR Expression in Health and Disease

le Daujat-Chavanieu, Martine, Gerbal-Chaloin, Sabine
Foilsithe in Cells (2020)

Primary hepatocytes isolated from human and porcine donors display similar patterns of cytochrome p450 expression following exposure to prototypical activators of AhR, CAR and PXR

le Gerbal-Chaloin, Sabine, Briolotti, Philippe, Daujat-Chavanieu, Martine, Rasmussen, Martin Krøyer
Foilsithe in Curr Res Toxicol (2021)

Chromatin Dynamics of Gene Activation and Repression in Response to Interferon α (IFNα) Reveal New Roles for Phosphorylated and Unphosphorylated Forms of the Transcription Factor S...

le Testoni, Barbara, Völlenkle, Christine, Guerrieri, Francesca, Gerbal-Chaloin, Sabine, Blandino, Giovanni, Levrero, Massimo
Foilsithe 2011

Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes

le Rasmussen, Martin Krøyer, Balaguer, Patrick, Ekstrand, Bo, Daujat-Chavanieu, Martine, Gerbal-Chaloin, Sabine
Foilsithe in PLoS One (2016)

Comparison of Hepatic-like Cell Production from Human Embryonic Stem Cells and Adult Liver Progenitor Cells: CAR Transduction Activates a Battery of Detoxification Genes

le Funakoshi, Natalie, Duret, Cédric, Pascussi, Jean-Marc, Blanc, Pierre, Maurel, Patrick, Daujat-Chavanieu, Martine, Gerbal-Chaloin, Sabine
Foilsithe 2011

The pregnane X receptor down‐regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for (“squelching”) SRC‐1 coactivator

le Hyrsova, Lucie, Smutny, Tomas, Carazo, Alejandro, Moravcik, Stefan, Mandikova, Jana, Trejtnar, Frantisek, Gerbal‐Chaloin, Sabine, Pavek, Petr
Foilsithe in Br J Pharmacol (2016)

The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids

le Smutny, Tomas, Dusek, Jan, Hyrsova, Lucie, Nekvindova, Jana, Horvatova, Alzbeta, Micuda, Stanislav, Gerbal-Chaloin, Sabine, Pavek, Petr
Foilsithe in Acta Pharm Sin B (2020)

Human pluripotent stem cells: From biology to cell therapy

le Ramirez, Jean-Marie, Bai, Qiang, Dijon-Grinand, Marilyne, Assou, Said, Gerbal-Chaloin, Sabine, Hamamah, Samir, Vos, John De
Foilsithe 2010

MitoCeption: Transferring Isolated Human MSC Mitochondria to Glioblastoma Stem Cells

le Nzigou Mombo, Brice, Gerbal-Chaloin, Sabine, Bokus, Aleksandra, Daujat-Chavanieu, Martine, Jorgensen, Christian, Hugnot, Jean-Philippe, Vignais, Marie-Luce
Foilsithe in J Vis Exp (2017)

Dissecting the First Transcriptional Divergence During Human Embryonic Development

le Bai, Qiang, Assou, Said, Haouzi, Delphine, Ramirez, Jean-Marie, Monzo, Cécile, Becker, Fabienne, Gerbal-Chaloin, Sabine, Hamamah, Samir, De Vos, John
Foilsithe 2011

Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain

le Skoda, Josef, Dusek, Jan, Drastik, Martin, Stefela, Alzbeta, Dohnalova, Klara, Chalupsky, Karel, Smutny, Tomas, Micuda, Stanislav, Gerbal-Chaloin, Sabine, Pavek, Petr
Foilsithe in Cells (2020)

Modular bioreactor for primary human hepatocyte culture: Medium flow stimulates expression and activity of detoxification genes

le Vinci, Bruna, Duret, Cédric, Klieber, Sylvie, Gerbal-Chaloin, Sabine, Sa-Cunha, Antonio, Laporte, Sylvain, Suc, Bertrand, Maurel, Patrick, Ahluwalia, Arti, Daujat-Chavanieu, Martine
Foilsithe 2011

ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

le Riou, Rozenn, Ladli, Meriem, Gerbal-Chaloin, Sabine, Bossard, Pascale, Gougelet, Angélique, Godard, Cécile, Loesch, Robin, Lagoutte, Isabelle, Lager, Franck, Calderaro, Julien, Dos Santos, Alexandre, Wang, Zhong, Verdier, Frédérique, Colnot, Sabine
Foilsithe in eLife (2020)

The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor

le Creusot, Nicolas, Gassiot, Matthieu, Alaterre, Elina, Chiavarina, Barbara, Grimaldi, Marina, Boulahtouf, Abdelhay, Toporova, Lucia, Gerbal-Chaloin, Sabine, Daujat-Chavanieu, Martine, Matheux, Alice, Rahmani, Roger, Gongora, Céline, Evrard, Alexandre, Pourquier, Philippe, Balaguer, Patrick
Foilsithe in Cells (2020)

Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds

le Delfosse, Vanessa, Dendele, Béatrice, Huet, Tiphaine, Grimaldi, Marina, Boulahtouf, Abdelhay, Gerbal-Chaloin, Sabine, Beucher, Bertrand, Roecklin, Dominique, Muller, Christina, Rahmani, Roger, Cavaillès, Vincent, Daujat-Chavanieu, Martine, Vivat, Valérie, Pascussi, Jean-Marc, Balaguer, Patrick, Bourguet, William
Foilsithe in Nat Commun (2015)

The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway

le Khan, Abrar Ul Haq, Allende-Vega, Nerea, Gitenay, Delphine, Gerbal-Chaloin, Sabine, Gondeau, Claire, Vo, Dang-Nghiem, Belkahla, Sana, Orecchioni, Stefania, Talarico, Giovanna, Bertolini, Francesco, Bozic, Milica, Valdivielso, Jose M., Bejjani, Fabienne, Jariel, Isabelle, Lopez-Mejia, Isabel C., Fajas, Lluis, Lecellier, Charles-Henri, Hernandez, Javier, Daujat, Martine, Villalba, Martin
Foilsithe in Sci Rep (2017)

Mitochondrial Complex I activity signals antioxidant response through ERK5

le Khan, Abrar Ul Haq, Allende-Vega, Nerea, Gitenay, Delphine, Garaude, Johan, Vo, Dang-Nghiem, Belkhala, Sana, Gerbal-Chaloin, Sabine, Gondeau, Claire, Daujat-Chavanieu, Martine, Delettre, Cécile, Orecchioni, Stefania, Talarico, Giovanna, Bertolini, Francesco, Anel, Alberto, Cuezva, José M., Enriquez, Jose A., Cartron, Guillaume, Lecellier, Charles-Henri, Hernandez, Javier, Villalba, Martin
Foilsithe in Sci Rep (2018)