ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

Erythropoietin (EPO) is a key regulator of erythropoiesis. The embryonic liver is the main site of erythropoietin synthesis, after which the kidney takes over. The adult liver retains the ability to express EPO, and we discovered here new players of this transcription, distinct from the classical hy...

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Vydáno v:eLife
Hlavní autoři: Riou, Rozenn, Ladli, Meriem, Gerbal-Chaloin, Sabine, Bossard, Pascale, Gougelet, Angélique, Godard, Cécile, Loesch, Robin, Lagoutte, Isabelle, Lager, Franck, Calderaro, Julien, Dos Santos, Alexandre, Wang, Zhong, Verdier, Frédérique, Colnot, Sabine
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Chromosomes and Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641585/
https://ncbi.nlm.nih.gov/pubmed/33084574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53550
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