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MicroRNA-feedback loop as a key modulator of liver tumorigenesis and inflammation

A recent work of Iliopoulos et al published in Cell highlighted a circuit orchestrated by microRNAs (miRNAs) that results in liver tumorigenesis and inflammation. This feedback loop, governed by miR-24 and miR-629, promotes a hepatocyte nuclear factor-4α transient inhibition resulting in miR-124 ind...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gougelet, Angélique, Colnot, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Co., Limited 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558567/
https://ncbi.nlm.nih.gov/pubmed/23382622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v19.i4.440
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