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A microRNA feedback loop regulates global microRNA abundance during aging

Expression levels of many microRNAs (miRNAs) change during aging, notably declining globally in a number of organisms and tissues across taxa. However, little is known about the mechanisms or the biological relevance for this change. We investigated the network of genes that controls miRNA transcrip...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Inukai, Sachi, Pincus, Zachary, de Lencastre, Alexandre, Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769744/
https://ncbi.nlm.nih.gov/pubmed/29114017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.062190.117
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