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A microRNA feedback loop regulates global microRNA abundance during aging

Expression levels of many microRNAs (miRNAs) change during aging, notably declining globally in a number of organisms and tissues across taxa. However, little is known about the mechanisms or the biological relevance for this change. We investigated the network of genes that controls miRNA transcrip...

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Publicat a:RNA
Autors principals: Inukai, Sachi, Pincus, Zachary, de Lencastre, Alexandre, Slack, Frank J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769744/
https://ncbi.nlm.nih.gov/pubmed/29114017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.062190.117
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