Snail-Modulated MicroRNA 493 Forms a Negative Feedback Loop with the Insulin-Like Growth Factor 1 Receptor Pathway and Blocks Tumorigenesis

In this study, we have identified one microRNA, microRNA 493 (miR-493), which could simultaneously and directly regulate multiple genes downstream of the insulin-like growth factor 1 receptor (IGF1R) pathway, including IGF1R, by binding with complementary sequences in the 3′ untranslated region (UTR...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Kumar, Arathy S., Jagadeeshan, Sankar, Pitani, Ravi Shankar, Ramshankar, Vijayalakshmi, Venkitasamy, Kesavan, Venkatraman, Ganesh, Rayala, Suresh K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335515/
https://ncbi.nlm.nih.gov/pubmed/27956702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00510-16
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