The pregnane X receptor down‐regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for (“squelching”) SRC‐1 coactivator

Por Hyrsova, Lucie, Smutny, Tomas, Carazo, Alejandro, Moravcik, Stefan, Mandikova, Jana, Trejtnar, Frantisek, Gerbal‐Chaloin, Sabine, Pavek, Petr
Publicado no Br J Pharmacol (2016)

The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids

Por Smutny, Tomas, Dusek, Jan, Hyrsova, Lucie, Nekvindova, Jana, Horvatova, Alzbeta, Micuda, Stanislav, Gerbal-Chaloin, Sabine, Pavek, Petr
Publicado no Acta Pharm Sin B (2020)

Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug–Drug Interactions

Por Mandíková, Jana, Volková, Marie, Pávek, Petr, Navrátilová, Lucie, Hyršová, Lucie, Janeba, Zlatko, Pavlík, Jan, Bárta, Pavel, Trejtnar, František
Publicado no Front Pharmacol (2016)

Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling

Por Carazo, Alejandro, Dusek, Jan, Holas, Ondrej, Skoda, Josef, Hyrsova, Lucie, Smutny, Tomas, Soukup, Tomas, Dosedel, Martin, Pávek, Petr
Publicado no Front Pharmacol (2018)

Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats

Por Dolezelova, Eva, Prasnicka, Alena, Cermanova, Jolana, Carazo, Alejandro, Hyrsova, Lucie, Hroch, Milos, Mokry, Jaroslav, Adamcova, Michaela, Mrkvicova, Alena, Pavek, Petr, Micuda, Stanislav
Publicado no World J Gastroenterol (2017)