Structural dynamics of the monoamine transporter homologue LeuT from accelerated conformational sampling and channel analysis

Por Thomas, James R., Gedeon, Patrick C., Madura, Jeffry D.
Publicado em 2014

Accelerated Molecular Dynamics and Protein Conformational Change: A Theoretical and Practical Guide Using a Membrane Embedded Model Neurotransmitter Transporter

Por Gedeon, Patrick C., Thomas, James R., Madura, Jeffry D.
Publicado no Methods Mol Biol (2015)

LeuT Conformational Sampling Utilizing Accelerated Molecular Dynamics and Principal Component Analysis

Por Thomas, James R., Gedeon, Patrick C., Grant, Barry J., Madura, Jeffry D.
Publicado em 2012

Antibody-based immunotherapy for malignant glioma

Por Gedeon, Patrick C., Riccione, Katherine A., Fecci, Peter E., Sampson, John H.
Publicado em 2014

Rindopepimut: anti-EGFRvIII peptide vaccine, oncolytic

Por Gedeon, Patrick C., Choi, Bryan D., Sampson, John H., Bigner, Darell D.
Publicado no Drugs Future (2013)

Structure and Dynamics Study of LeuT Using the Markov State Model and Perturbation Response Scanning Reveals Distinct Ion Induced Conformational States

Por Asciutto, Eliana K., Gedeon, Patrick C., General, Ignacio J., Madura, Jeffry D.
Publicado no J Phys Chem B (2016)

Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody

Por Choi, Bryan D, Gedeon, Patrick C, Sanchez-Perez, Luis, Bigner, Darell D, Sampson, John H
Publicado em 2013

Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma

Por Choi, Bryan D., Suryadevara, Carter M., Gedeon, Patrick C., Herndon, James E., Sanchez-Perez, Luis, Sampson, John H.
Publicado em 2013

An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma

Por Gedeon, Patrick C, Choi, Bryan D, Hodges, Tiffany R, Mitchell, Duane A, Bigner, Darell D, Sampson, John H
Publicado em 2013

Rational design and generation of recombinant control reagents for bispecific antibodies through CDR mutagenesis

Por Choi, Bryan D., Gedeon, Patrick C., Kuan, Chien-Tsun, Sanchez-Perez, Luis, Archer, Gary E., Bigner, Darell D., Sampson, John H.
Publicado em 2013

Epidermal growth factor receptor and variant III targeted immunotherapy

Por Congdon, Kendra L., Gedeon, Patrick C., Suryadevara, Carter M., Caruso, Hillary G., Cooper, Laurence J.N., Heimberger, Amy B., Sampson, John H.
Publicado em 2014

Are BiTEs the “missing link” in cancer therapy?

Por Suryadevara, Carter M, Gedeon, Patrick C, Sanchez-Perez, Luis, Verla, Terence, Alvarez-Breckenridge, Christopher, Choi, Bryan D, Fecci, Peter E, Sampson, John H
Publicado no Oncoimmunology (2015)

Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody

Por Choi, Bryan D., Gedeon, Patrick C., Herndon, James E., Archer, Gary E., Reap, Elizabeth A., Sanchez-Perez, Luis, Mitchell, Duane A., Bigner, Darell D., Sampson, John H.
Publicado em 2013

Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma

Por Choi, Bryan D., Kuan, Chien-Tsun, Cai, Mingqing, Archer, Gary E., Mitchell, Duane A., Gedeon, Patrick C., Sanchez-Perez, Luis, Pastan, Ira, Bigner, Darell D., Sampson, John H.
Publicado em 2013

Dendritic cells enhance polyfunctionality of adoptively transferred T cells which target cytomegalovirus in glioblastoma

Por Reap, Elizabeth A., Suryadevara, Carter M., Batich, Kristen A., Sanchez-Perez, Luis, Archer, Gary E., Schmittling, Robert J., Norberg, Pamela K., Herndon, James E., Healy, Patrick, Congdon, Kendra L., Gedeon, Patrick C., Campbell, Olivia C., Swartz, Adam M., Riccione, Katherine A., Yi, John S., Hossain-Ibrahim, Mohammed K., Saraswathula, Anirudh, Nair, Smita K., Dunn-Pirio, Anastasie M., Broome, Taylor M., Weinhold, Kent J., Desjardins, Annick, Vlahovic, Gordana, McLendon, Roger E., Friedman, Allan H., Friedman, Henry S., Bigner, Darell D., Fecci, Peter E., Mitchell, Duane A., Sampson, John H.
Publicado no Cancer Res (2017)