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Structural dynamics of the monoamine transporter homologue LeuT from accelerated conformational sampling and channel analysis

The bacterial leucine transporter LeuT retains significant secondary structure similarities to the human monoamine transporters (MAT) such as the dopamine and serotonin reuptake proteins. The primary method of computational study of the MATs has been through the use of the crystallized LeuT structur...

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Detalhes bibliográficos
Main Authors: Thomas, James R., Gedeon, Patrick C., Madura, Jeffry D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177338/
https://ncbi.nlm.nih.gov/pubmed/24753369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24588
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