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LeuT Conformational Sampling Utilizing Accelerated Molecular Dynamics and Principal Component Analysis
Monoamine transporters (MATs) function by coupling ion gradients to the transport of dopamine, norepinephrine, or serotonin. Despite their importance in regulating neurotransmission, the exact conformational mechanism by which MATs function remains elusive. To this end, we have performed seven 250 n...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388204/ https://ncbi.nlm.nih.gov/pubmed/22828348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.002 |
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