Regulatory T cells move in when gliomas say “I-DO”

Por Choi, Bryan D., Fecci, Peter E., Sampson, John H.
Publicado em 2012

A novel bispecific antibody recruits T cells to eradicate tumors in the “immunologically privileged” central nervous system

Por Choi, Bryan D., Pastan, Ira, Bigner, Darell D., Sampson, John H.
Publicado em 2013

Rindopepimut: anti-EGFRvIII peptide vaccine, oncolytic

Por Gedeon, Patrick C., Choi, Bryan D., Sampson, John H., Bigner, Darell D.
Publicado no Drugs Future (2013)

Isocitrate dehydrogenase 1 (IDH1): what it means to the neurosurgeon

Por Hodges, Tiffany R., Choi, Bryan D., Bigner, Darell D., Yan, Hai, Sampson, John H.
Publicado em 2013

Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody

Por Choi, Bryan D, Gedeon, Patrick C, Sanchez-Perez, Luis, Bigner, Darell D, Sampson, John H
Publicado em 2013

Leveraging chemotherapy-induced lymphopenia to potentiate cancer immunotherapy

Por Sanchez-Perez, Luis, Suryadevara, Carter M, Choi, Bryan D, Reap, Elizabeth A, Sampson, John H
Publicado no Oncoimmunology (2014)

Enzyme Redesign Guided by Cancer-Derived IDH1 Mutations

Por Reitman, Zachary J., Choi, Bryan D., Spasojevic, Ivan, Bigner, Darell D., Sampson, John H., Yan, Hai
Publicado em 2012

Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma

Por Choi, Bryan D., Suryadevara, Carter M., Gedeon, Patrick C., Herndon, James E., Sanchez-Perez, Luis, Sampson, John H.
Publicado em 2013

An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma

Por Gedeon, Patrick C, Choi, Bryan D, Hodges, Tiffany R, Mitchell, Duane A, Bigner, Darell D, Sampson, John H
Publicado em 2013

Immunotherapy for malignant glioma

Por Suryadevara, Carter M., Verla, Terence, Sanchez-Perez, Luis, Reap, Elizabeth A., Choi, Bryan D., Fecci, Peter E., Sampson, John H.
Publicado no Surg Neurol Int (2015)

Imaging of Convection Enhanced Delivery of Toxins in Humans

Por Mehta, Ankit I., Choi, Bryan D., Raghavan, Raghu, Brady, Martin, Friedman, Allan H., Bigner, Darell D., Pastan, Ira, Sampson, John H.
Publicado em 2011

Rational design and generation of recombinant control reagents for bispecific antibodies through CDR mutagenesis

Por Choi, Bryan D., Gedeon, Patrick C., Kuan, Chien-Tsun, Sanchez-Perez, Luis, Archer, Gary E., Bigner, Darell D., Sampson, John H.
Publicado em 2013

EGFRvIII‐Targeted Vaccination Therapy of Malignant Glioma

Por Choi, Bryan D., Archer, Gary E., Mitchell, Duane A., Heimberger, Amy B., McLendon, Roger E., Bigner, Darell D., Sampson, John H.
Publicado em 2009

Are BiTEs the “missing link” in cancer therapy?

Por Suryadevara, Carter M, Gedeon, Patrick C, Sanchez-Perez, Luis, Verla, Terence, Alvarez-Breckenridge, Christopher, Choi, Bryan D, Fecci, Peter E, Sampson, John H
Publicado no Oncoimmunology (2015)

Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody

Por Choi, Bryan D., Gedeon, Patrick C., Herndon, James E., Archer, Gary E., Reap, Elizabeth A., Sanchez-Perez, Luis, Mitchell, Duane A., Bigner, Darell D., Sampson, John H.
Publicado em 2013

Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma

Por Choi, Bryan D., Kuan, Chien-Tsun, Cai, Mingqing, Archer, Gary E., Mitchell, Duane A., Gedeon, Patrick C., Sanchez-Perez, Luis, Pastan, Ira, Bigner, Darell D., Sampson, John H.
Publicado em 2013

Myeloablative Temozolomide Enhances CD8(+) T-Cell Responses to Vaccine and Is Required for Efficacy against Brain Tumors in Mice

Por Sanchez-Perez, Luis A., Choi, Bryan D., Archer, Gary E., Cui, Xiuyu, Flores, Catherine, Johnson, Laura A., Schmittling, Robert J., Snyder, David, Herndon, James E., Bigner, Darell D., Mitchell, Duane A., Sampson, John H.
Publicado em 2013

Serum elevation of B lymphocyte stimulator does not increase regulatory B cells in glioblastoma patients undergoing immunotherapy

Por Saraswathula, Anirudh, Reap, Elizabeth A., Choi, Bryan D., Schmittling, Robert J., Norberg, Pamela K., Sayour, Elias J., Herndon, James E., Healy, Patrick, Congdon, Kendra L., Archer, Gerald E., Sanchez-Perez, Luis, Sampson, John H.
Publicado no Cancer Immunol Immunother (2016)

BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomide

Por Sanchez-Perez, Luis, Choi, Bryan D., Reap, Elizabeth A., Sayour, Elias J., Norberg, Pamela, Schmittling, Robert J., Archer, Gerald E., Herndon, James E., Mitchell, Duane A., Heimberger, Amy B., Bigner, Darell D., Sampson, John H.
Publicado em 2013

EGFRvIII-Specific Chimeric Antigen Receptor T Cells Migrate to and Kill Tumor Deposits Infiltrating the Brain Parenchyma in an Invasive Xenograft Model of Glioblastoma

Por Miao, Hongsheng, Choi, Bryan D., Suryadevara, Carter M., Sanchez-Perez, Luis, Yang, Shicheng, De Leon, Gabriel, Sayour, Elias J., McLendon, Roger, Herndon, James E., Healy, Patrick, Archer, Gary E., Bigner, Darell D., Johnson, Laura A., Sampson, John H.
Publicado em 2014