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Isocitrate dehydrogenase 1 (IDH1): what it means to the neurosurgeon

Isocitrate dehydrogenase-1 (IDH1) mutations have been discovered to be frequent and highly conserved in secondary glioblastoma (GBM) and lower grade gliomas. Although IDH1 mutations confer a unique genotype that has been associated with a favorable prognosis, the role of the mutated IDH1 enzyme and...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Hodges, Tiffany R., Choi, Bryan D., Bigner, Darell D., Yan, Hai, Sampson, John H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672384/
https://ncbi.nlm.nih.gov/pubmed/23581583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2013.3.JNS122282
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