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Isocitrate dehydrogenase 1 (IDH1): what it means to the neurosurgeon
Isocitrate dehydrogenase-1 (IDH1) mutations have been discovered to be frequent and highly conserved in secondary glioblastoma (GBM) and lower grade gliomas. Although IDH1 mutations confer a unique genotype that has been associated with a favorable prognosis, the role of the mutated IDH1 enzyme and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672384/ https://ncbi.nlm.nih.gov/pubmed/23581583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2013.3.JNS122282 |
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