Cholesterol Accumulation Sequesters Rab9 and Disrupts Late Endosome Function in NPC1-deficient Cells

Por Ganley, Ian G., Pfeffer, Suzanne R.
Publicado em 2006

MTOR, PIK3C3, and autophagy: Signaling the beginning from the end

Por Munson, Michael J, Ganley, Ian G
Publicado no Autophagy (2015)

Determination of Cellular Phosphatidylinositol-3-phosphate (PI3P) Levels Using a Fluorescently Labelled Selective PI3P Binding Domain (PX)

Por Munson, Michael J., Ganley, Ian G.
Publicado no Bio Protoc (2016)

Determination of VPS34/PIK3C3 Activity in vitro Utilising (32)P-γATP

Por Munson, Michael J., Ganley, Ian G.
Publicado no Bio Protoc (2016)

Life in lights: Tracking mitochondrial delivery to lysosomes in vivo

Por McWilliams, Thomas G., Ganley, Ian G.
Publicado no Autophagy (2016)

A syntaxin 10–SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells

Por Ganley, Ian G., Espinosa, Eric, Pfeffer, Suzanne R.
Publicado em 2008

Rab9 GTPase Regulates Late Endosome Size and Requires Effector Interaction for Its Stability

Por Ganley, Ian G., Carroll, Kate, Bittova, Lenka, Pfeffer, Suzanne
Publicado em 2004

Clues to Neuro-Degeneration in Niemann-Pick Type C Disease from Global Gene Expression Profiling

Por Reddy, Jonathan V., Ganley, Ian G., Pfeffer, Suzanne R.
Publicado em 2006

DISTINCT AUTOPHAGOSOMAL-LYSOSOMAL FUSION MECHANISM REVEALED BY THAPSIGARGIN-INDUCED AUTOPHAGY ARREST

Por Ganley, Ian G., Wong, Pui-Mun, Gammoh, Noor, Jiang, Xuejun
Publicado em 2011

The ULK1 complex: Sensing nutrient signals for autophagy activation

Por Wong, Pui-Mun, Puente, Cindy, Ganley, Ian G., Jiang, Xuejun
Publicado em 2013

Loss of iron triggers PINK1/Parkin-independent mitophagy

Por Allen, George F G, Toth, Rachel, James, John, Ganley, Ian G
Publicado em 2013

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

Por Ganley, Ian G., Lam, Du H., Wang, Junru, Ding, Xiaojun, Chen, She, Jiang, Xuejun
Publicado em 2009

RUTBC1 Protein, a Rab9A Effector That Activates GTP Hydrolysis by Rab32 and Rab33B Proteins

Por Nottingham, Ryan M., Ganley, Ian G., Barr, Francis A., Lambright, David G., Pfeffer, Suzanne R.
Publicado em 2011

A Functional Role for the GCC185 Golgin in Mannose 6-Phosphate Receptor Recycling

Por Reddy, Jonathan V., Burguete, Alondra Schweizer, Sridevi, Khambhampaty, Ganley, Ian G., Nottingham, Ryan M., Pfeffer, Suzanne R.
Publicado em 2006

mTOR activates the VPS34–UVRAG complex to regulate autolysosomal tubulation and cell survival

Por Munson, Michael J, Allen, George FG, Toth, Rachel, Campbell, David G, Lucocq, John M, Ganley, Ian G
Publicado no EMBO J (2015)

RUTBC2 Protein, a Rab9A Effector and GTPase-activating Protein for Rab36

Por Nottingham, Ryan M., Pusapati, Ganesh V., Ganley, Ian G., Barr, Francis A., Lambright, David G., Pfeffer, Suzanne R.
Publicado em 2012

GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

Por Stretton, Clare, Hoffmann, Thorsten M., Munson, Michael J., Prescott, Alan, Taylor, Peter M., Ganley, Ian G., Hundal, Harinder S.
Publicado no Biochem J (2015)

Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy

Por Petherick, Katy J., Conway, Owen J. L., Mpamhanga, Chido, Osborne, Simon A., Kamal, Ahmad, Saxty, Barbara, Ganley, Ian G.
Publicado no J Biol Chem (2015)

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy.

Por Petherick, Katy J., Conway, Owen J. L., Mpamhanga, Chido, Osborne, Simon A., Kamal, Ahmad, Saxty, Barbara, Ganley, Ian G.
Publicado no J Biol Chem (2015)

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

Por Hau, Andrew M., Greenwood, Jeffrey A., Löhr, Christiane V., Serrill, Jeffrey D., Proteau, Philip J., Ganley, Ian G., McPhail, Kerry L., Ishmael, Jane E.
Publicado em 2013