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DISTINCT AUTOPHAGOSOMAL-LYSOSOMAL FUSION MECHANISM REVEALED BY THAPSIGARGIN-INDUCED AUTOPHAGY ARREST
Autophagy, a catabolic pathway that delivers cellular components to lysosomes for degradation, can be activated by stressful conditions such as nutrient starvation and endoplasmic reticulum (ER) stress. We report that thapsigargin, an ER stressor widely used to induce autophagy, in fact blocks autop...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124681/ https://ncbi.nlm.nih.gov/pubmed/21700220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.04.024 |
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