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The ULK1 complex: Sensing nutrient signals for autophagy activation

The Atg1/ULK1 complex plays a central role in starvation-induced autophagy, integrating signals from upstream sensors such as MTOR and AMPK and transducing them to the downstream autophagy pathway. Much progress has been made in the last few years in understanding the mechanisms by which the complex...

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Bibliografiske detaljer
Main Authors: Wong, Pui-Mun, Puente, Cindy, Ganley, Ian G., Jiang, Xuejun
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552878/
https://ncbi.nlm.nih.gov/pubmed/23295650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23323
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