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The mammalian ULK1 complex and autophagy initiation

Autophagy is a vital lysosomal degradation pathway that serves as a quality control mechanism. It rids the cell of damaged, toxic or excess cellular components, which if left to persist could be detrimental to the cell. It also serves as a recycling pathway to maintain protein synthesis under starva...

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Detalhes bibliográficos
Publicado no:Essays Biochem
Main Authors: Zachari, Maria, Ganley, Ian G.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869855/
https://ncbi.nlm.nih.gov/pubmed/29233870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20170021
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