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ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
Autophagy is a degradative process that recycles long-lived and faulty cellular components. It is linked to many diseases and is required for normal development. ULK1, a mammalian serine/threonine protein kinase, plays a key role in the initial stages of autophagy, though the exact molecular mechani...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673298/ https://ncbi.nlm.nih.gov/pubmed/19258318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900573200 |
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