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ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

Autophagy is a degradative process that recycles long-lived and faulty cellular components. It is linked to many diseases and is required for normal development. ULK1, a mammalian serine/threonine protein kinase, plays a key role in the initial stages of autophagy, though the exact molecular mechani...

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Detalhes bibliográficos
Main Authors: Ganley, Ian G., Lam, Du H., Wang, Junru, Ding, Xiaojun, Chen, She, Jiang, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673298/
https://ncbi.nlm.nih.gov/pubmed/19258318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900573200
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