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ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Autophagy, the starvation-induced degradation of bulky cytosolic components, is up-regulated in mammalian cells when nutrient supplies are limited. Although mammalian target of rapamycin (mTOR) is known as the key regulator of autophagy induction, the mechanism by which mTOR regulates autophagy has...

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Bibliografische gegevens
Hoofdauteurs: Jung, Chang Hwa, Jun, Chang Bong, Ro, Seung-Hyun, Kim, Young-Mi, Otto, Neil Michael, Cao, Jing, Kundu, Mondira, Kim, Do-Hyung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663920/
https://ncbi.nlm.nih.gov/pubmed/19225151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-12-1249
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