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ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Autophagy, the starvation-induced degradation of bulky cytosolic components, is up-regulated in mammalian cells when nutrient supplies are limited. Although mammalian target of rapamycin (mTOR) is known as the key regulator of autophagy induction, the mechanism by which mTOR regulates autophagy has...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663920/ https://ncbi.nlm.nih.gov/pubmed/19225151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-12-1249 |
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