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ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Autophagy, the starvation-induced degradation of bulky cytosolic components, is up-regulated in mammalian cells when nutrient supplies are limited. Although mammalian target of rapamycin (mTOR) is known as the key regulator of autophagy induction, the mechanism by which mTOR regulates autophagy has...

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Autors principals: Jung, Chang Hwa, Jun, Chang Bong, Ro, Seung-Hyun, Kim, Young-Mi, Otto, Neil Michael, Cao, Jing, Kundu, Mondira, Kim, Do-Hyung
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663920/
https://ncbi.nlm.nih.gov/pubmed/19225151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-12-1249
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