Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction

Under normal growth conditions the mammalian target of rapamycin complex 1 (mTORC1) negatively regulates the central autophagy regulator complex consisting of Unc-51-like kinases 1/2 (Ulk1/2), focal adhesion kinase family-interacting protein of 200 kDa (FIP200) and Atg13. Upon starvation, mTORC1-med...

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Autors principals: Alers, Sebastian, Löffler, Antje S., Paasch, Florian, Dieterle, Alexandra M., Keppeler, Hildegard, Lauber, Kirsten, Campbell, David G., Fehrenbacher, Birgit, Schaller, Martin, Wesselborg, Sebastian, Stork, Björn
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Basic Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327613/
https://ncbi.nlm.nih.gov/pubmed/22024743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.18027
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