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Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction
Under normal growth conditions the mammalian target of rapamycin complex 1 (mTORC1) negatively regulates the central autophagy regulator complex consisting of Unc-51-like kinases 1/2 (Ulk1/2), focal adhesion kinase family-interacting protein of 200 kDa (FIP200) and Atg13. Upon starvation, mTORC1-med...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327613/ https://ncbi.nlm.nih.gov/pubmed/22024743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.18027 |
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