Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

Autophagy is an intracellular degradation system, by which cytoplasmic contents are degraded in lysosomes. Autophagy is dynamically induced by nutrient depletion to provide necessary amino acids within cells, thus helping them adapt to starvation. Although it has been suggested that mTOR is a major...

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Autores principales: Hosokawa, Nao, Hara, Taichi, Kaizuka, Takeshi, Kishi, Chieko, Takamura, Akito, Miura, Yutaka, Iemura, Shun-ichiro, Natsume, Tohru, Takehana, Kenji, Yamada, Naoyuki, Guan, Jun-Lin, Oshiro, Noriko, Mizushima, Noboru
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663915/
https://ncbi.nlm.nih.gov/pubmed/19211835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-12-1248
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