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Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly
Mammalian target of rapamycin (mTOR) is a member of the phosphatidylinositol 3-kinase-related kinase (PIKK) family and is a major regulator of translation, cell growth, and autophagy. mTOR exists in two distinct complexes, mTORC1 and mTORC2, that differ in their subunit composition. In this study, w...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888423/ https://ncbi.nlm.nih.gov/pubmed/20427287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.121699 |
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