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Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly

Mammalian target of rapamycin (mTOR) is a member of the phosphatidylinositol 3-kinase-related kinase (PIKK) family and is a major regulator of translation, cell growth, and autophagy. mTOR exists in two distinct complexes, mTORC1 and mTORC2, that differ in their subunit composition. In this study, w...

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Main Authors: Kaizuka, Takeshi, Hara, Taichi, Oshiro, Noriko, Kikkawa, Ushio, Yonezawa, Kazuyoshi, Takehana, Kenji, Iemura, Shun-ichiro, Natsume, Tohru, Mizushima, Noboru
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888423/
https://ncbi.nlm.nih.gov/pubmed/20427287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.121699
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