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Suppression of p53 Activity through the Cooperative Action of Ski and Histone Deacetylase SIRT1

Ski was originally identified as an oncogene based on the fact that Ski overexpression transformed chicken and quail embryo fibroblasts. Consistent with these proposed oncogenic roles, Ski is overexpressed in various human tumors. However, whether and how Ski functions in mammalian tumorigenesis has...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Inoue, Yasumichi, Iemura, Shun-ichiro, Natsume, Tohru, Miyazawa, Keiji, Imamura, Takeshi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057854/
https://ncbi.nlm.nih.gov/pubmed/21149449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177683
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