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Regulation of MyD88 Aggregation and the MyD88-dependent Signaling Pathway by Sequestosome 1 and Histone Deacetylase 6

MyD88 is an essential adaptor molecule for Toll-like receptors (TLRs) and interleukin (IL)-1 receptor. MyD88 is thought to be present as condensed forms or aggregated structures in the cytoplasm, although the reason has not yet been clear. Here, we show that endogenous MyD88 is present as small spec...

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Detalhes bibliográficos
Main Authors: Into, Takeshi, Inomata, Megumi, Niida, Shumpei, Murakami, Yukitaka, Shibata, Ken-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975200/
https://ncbi.nlm.nih.gov/pubmed/20837465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126904
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