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Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88

Autophagy, the processes of delivery of intracellular components to lysosomes, regulates induction of inflammation. Inducible macroautophagy degrades inflammasomes and dysfunctional mitochondria to downregulate inflammatory signals. Nonetheless, the effects of constitutive basal autophagy on inflamm...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Into, Takeshi, Horie, Toshi, Inomata, Megumi, Gohda, Jin, Inoue, Jun-ichiro, Murakami, Yukitaka, Niida, Shumpei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430896/
https://ncbi.nlm.nih.gov/pubmed/28432355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01246-w
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