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Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88
Autophagy, the processes of delivery of intracellular components to lysosomes, regulates induction of inflammation. Inducible macroautophagy degrades inflammasomes and dysfunctional mitochondria to downregulate inflammatory signals. Nonetheless, the effects of constitutive basal autophagy on inflamm...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5430896/ https://ncbi.nlm.nih.gov/pubmed/28432355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01246-w |
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