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Interaction Between FIP200 and ATG16L1 Distinguishes ULK1 Complex-Dependent and -Independent Autophagy

Autophagy is a finely orchestrated cellular catabolic process that requires multiple autophagy-related gene products (ATG). The ULK1 complex functions to integrate upstream signals to downstream ATG proteins through an unknown mechanism. Here, we identified an interaction between mammalian FIP200 an...

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Détails bibliographiques
Auteurs principaux: Gammoh, Noor, Florey, Oliver, Overholtzer, Michael, Jiang, Xuejun
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565010/
https://ncbi.nlm.nih.gov/pubmed/23262492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2475
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