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mTOR activates the VPS34–UVRAG complex to regulate autolysosomal tubulation and cell survival
Lysosomes are essential organelles that function to degrade and recycle unwanted, damaged and toxic biological components. Lysosomes also act as signalling platforms in activating the nutrient-sensing kinase mTOR. mTOR regulates cellular growth, but it also helps to maintain lysosome identity by ini...
Enregistré dans:
| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley & Sons, Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4585463/ https://ncbi.nlm.nih.gov/pubmed/26139536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201590992 |
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