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WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
WHAMM, a member of the Wiskott-Aldrich syndrome protein (WASP) family, is an actin nucleation promoting factor (NPF) that also associates with membranes and microtubules. Here we report that WHAMM is required for autophagic lysosome reformation (ALR). WHAMM knockout causes impairment of autolysosome...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697732/ https://ncbi.nlm.nih.gov/pubmed/31420534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11694-9 |
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