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WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
WHAMM, a member of the Wiskott-Aldrich syndrome protein (WASP) family, is an actin nucleation promoting factor (NPF) that also associates with membranes and microtubules. Here we report that WHAMM is required for autophagic lysosome reformation (ALR). WHAMM knockout causes impairment of autolysosome...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697732/ https://ncbi.nlm.nih.gov/pubmed/31420534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11694-9 |
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