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WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes
WHAMM, a member of the Wiskott-Aldrich syndrome protein (WASP) family, is an actin nucleation promoting factor (NPF) that also associates with membranes and microtubules. Here we report that WHAMM is required for autophagic lysosome reformation (ALR). WHAMM knockout causes impairment of autolysosome...
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| Udgivet i: | Nat Commun |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697732/ https://ncbi.nlm.nih.gov/pubmed/31420534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11694-9 |
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