A Functional Role for the GCC185 Golgin in Mannose 6-Phosphate Receptor Recycling

Mannose 6-phosphate receptors (MPRs) deliver newly synthesized lysosomal enzymes to endosomes and then recycle to the Golgi. MPR recycling requires Rab9 GTPase; Rab9 recruits the cytosolic adaptor TIP47 and enhances its ability to bind to MPR cytoplasmic domains during transport vesicle formation. R...

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Hauptverfasser: Reddy, Jonathan V., Burguete, Alondra Schweizer, Sridevi, Khambhampaty, Ganley, Ian G., Nottingham, Ryan M., Pfeffer, Suzanne R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635343/
https://ncbi.nlm.nih.gov/pubmed/16885419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-02-0153
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