CLEC-2 and podoplanin, partners again

Por Fu, Jianxin, Xia, Lijun
Publicado no Blood (2016)

Mucin-type O-glycosylation is critical for vascular integrity

Por Herzog, Brett H, Fu, Jianxin, Xia, Lijun
Publicado em 2014

Identification of Suitable Reference Genes for Gene Expression Normalization in the Quantitative Real-Time PCR Analysis of Sweet Osmanthus (Osmanthus fragrans Lour.)

Por Zhang, Chao, Fu, Jianxin, Wang, Yiguang, Bao, Zhiyi, Zhao, Hongbo
Publicado no PLoS One (2015)

Loss of intestinal O-glycans promotes spontaneous duodenal tumors

Por Gao, Nan, Bergstrom, Kirk, Fu, Jianxin, Xie, Biao, Chen, Weichang, Xia, Lijun
Publicado no Am J Physiol Gastrointest Liver Physiol (2016)

Replacing the Promoter of the Murine Gene Encoding P-selectin with the Human Promoter Confers Human-like Basal and Inducible Expression in Mice

Por Liu, Zhenghui, Zhang, Nan, Shao, Bojing, Panicker, Sumith R., Fu, Jianxin, McEver, Rodger P.
Publicado no J Biol Chem (2016)

Core 1-derived O-glycans are essential E-selectin ligands on neutrophils

Por Yago, Tadayuki, Fu, Jianxin, McDaniel, J. Michael, Miner, Jonathan J., McEver, Rodger P., Xia, Lijun
Publicado em 2010

Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma

Por Song, Kai, Herzog, Brett H., Sheng, Minjia, Fu, Jianxin, McDaniel, J. Michael, Ruan, Jia, Xia, Lijun
Publicado em 2013

Lymph flow regulates collecting lymphatic vessel maturation in vivo

Por Sweet, Daniel T., Jiménez, Juan M., Chang, Jeremy, Hess, Paul R., Mericko-Ishizuka, Patricia, Fu, Jianxin, Xia, Lijun, Davies, Peter F., Kahn, Mark L.
Publicado no J Clin Invest (2015)

O-glycans direct selectin ligands to lipid rafts on leukocytes

Por Shao, Bojing, Yago, Tadayuki, Setiadi, Hendra, Wang, Ying, Mehta-D’souza, Padmaja, Fu, Jianxin, Crocker, Paul R., Rodgers, William, Xia, Lijun, McEver, Rodger P.
Publicado no Proc Natl Acad Sci U S A (2015)

Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice

Por Song, Kai, Herzog, Brett H., Fu, Jianxin, Sheng, Minjia, Bergstrom, Kirk, McDaniel, J. Michael, Kondo, Yuji, McGee, Samuel, Cai, Xiaofeng, Li, Ping, Chen, Hong, Xia, Lijun
Publicado no J Biol Chem (2015)

Discordance between changes in the gut microbiota and pathogenicity in a mouse model of spontaneous colitis

Por Perez-Muñoz, Maria Elisa, Bergstrom, Kirk, Peng, Vincent, Schmaltz, Robert, Jimenez-Cardona, Roberto, Marsteller, Nathan, McGee, Sam, Clavel, Thomas, Ley, Ruth, Fu, Jianxin, Xia, Lijun, Peterson, Daniel A
Publicado em 2014

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life

Por Hess, Paul R., Rawnsley, David R., Jakus, Zoltán, Yang, Yiqing, Sweet, Daniel T., Fu, Jianxin, Herzog, Brett, Lu, MinMin, Nieswandt, Bernhard, Oliver, Guillermo, Makinen, Taija, Xia, Lijun, Kahn, Mark L.
Publicado em 2013

Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3

Por Chen, Wei-Sheng, Cao, Zhiyi, Sugaya, Satoshi, Lopez, Maria J., Sendra, Victor G., Laver, Nora, Leffler, Hakon, Nilsson, Ulf J., Fu, Jianxin, Song, Jianhua, Xia, Lijun, Hamrah, Pedram, Panjwani, Noorjahan
Publicado no Nat Commun (2016)

Erratum: Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3

Por Chen, Wei-Sheng, Cao, Zhiyi, Sugaya, Satoshi, Lopez, Maria J., Sendra, Victor G., Laver, Nora, Leffler, Hakon, Nilsson, Ulf J., Fu, Jianxin, Song, Jianhua, Xia, Lijun, Hamrah, Pedram, Panjwani, Noorjahan
Publicado no Nat Commun (2016)

Core 1- and core 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice

Por Bergstrom, Kirk, Fu, Jianxin, Johansson, Malin EV, Liu, Xiaowei, Gao, Nan, Wu, Qian, Song, Jianhua, McDaniel, J Michael, McGee, Samuel, Chen, Weichang, Braun, Jonathan, Hansson, Gunnar C, Xia, Lijun
Publicado no Mucosal Immunol (2016)

Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets

Por Pan, Yanfang, Yago, Tadayuki, Fu, Jianxin, Herzog, Brett, McDaniel, J. Michael, Mehta-D’Souza, Padmaja, Cai, Xiaofeng, Ruan, Changgeng, McEver, Rodger P., West, Christopher, Dai, Kesheng, Chen, Hong, Xia, Lijun
Publicado no Blood (2014)

Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves

Por Cha, Boksik, Geng, Xin, Mahamud, Md. Riaj, Fu, Jianxin, Mukherjee, Anish, Kim, Yeunhee, Jho, Eek-hoon, Kim, Tae Hoon, Kahn, Mark L., Xia, Lijun, Dixon, J. Brandon, Chen, Hong, Srinivasan, R. Sathish
Publicado no Genes Dev (2016)

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

Por Fu, Jianxin, Gerhardt, Holger, McDaniel, J. Michael, Xia, Baoyun, Liu, Xiaowei, Ivanciu, Lacramioara, Ny, Annelii, Hermans, Karlien, Silasi-Mansat, Robert, McGee, Samuel, Nye, Emma, Ju, Tongzhong, Ramirez, Maria I., Carmeliet, Peter, Cummings, Richard D., Lupu, Florea, Xia, Lijun
Publicado em 2008

Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice

Por Fu, Jianxin, Wei, Bo, Wen, Tao, Johansson, Malin E.V., Liu, Xiaowei, Bradford, Emily, Thomsson, Kristina A., McGee, Samuel, Mansour, Lilah, Tong, Maomeng, McDaniel, J. Michael, Sferra, Thomas J., Turner, Jerrold R., Chen, Hong, Hansson, Gunnar C., Braun, Jonathan, Xia, Lijun
Publicado em 2011

The CLEC-2–podoplanin axis controls fibroblastic reticular cell contractility and lymph node microarchitecture

Por Astarita, Jillian L., Cremasco, Viviana, Fu, Jianxin, Darnell, Max C., Peck, James R., Nieves-Bonilla, Janice M., Song, Kai, Woodruff, Matthew C., Gogineni, Alvin, Onder, Lucas, Ludewig, Burkhard, Weimer, Robby M., Carroll, Michael C., Mooney, David J., Xia, Lijun, Turley, Shannon J.
Publicado no Nat Immunol (2014)