Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice

Mucin-type core 1-derived O-glycans, one of the major types of O-glycans, are highly expressed in mammary gland epithelium. Abnormal O-glycans such as Tn antigen are found in over 90% of breast cancers; however, the in vivo role of these aberrant O-glycans in the etiology of breast cancer is unclear...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Song, Kai, Herzog, Brett H., Fu, Jianxin, Sheng, Minjia, Bergstrom, Kirk, McDaniel, J. Michael, Kondo, Yuji, McGee, Samuel, Cai, Xiaofeng, Li, Ping, Chen, Hong, Xia, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536426/
https://ncbi.nlm.nih.gov/pubmed/26124270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654483
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