Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney

The kidney's filtration activity is essential for removing toxins and waste products from the body. The vascular endothelial cells of the glomerulus are fenestrated, flattened, and surrounded by podocytes, specialized cells that support glomerular endothelial cells. Mucin-type core 1–derived O-...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Song, Kai, Fu, Jianxin, Song, Jianhua, Herzog, Brett H., Bergstrom, Kirk, Kondo, Yuji, McDaniel, J. Michael, McGee, Samuel, Silasi-Mansat, Robert, Lupu, Florea, Chen, Hong, Bagavant, Harini, Xia, Lijun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633109/
https://ncbi.nlm.nih.gov/pubmed/28842487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.798512
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