Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets

O-glycosylation of podoplanin (PDPN) on lymphatic endothelial cells is critical for the separation of blood and lymphatic systems by interacting with platelet C-type lectin-like receptor 2 during development. However, how O-glycosylation controls endothelial PDPN function and expression remains uncl...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Pan, Yanfang, Yago, Tadayuki, Fu, Jianxin, Herzog, Brett, McDaniel, J. Michael, Mehta-D’Souza, Padmaja, Cai, Xiaofeng, Ruan, Changgeng, McEver, Rodger P., West, Christopher, Dai, Kesheng, Chen, Hong, Xia, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256915/
https://ncbi.nlm.nih.gov/pubmed/25336627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-572107
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