PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line

door Kumar, Vipul, Alt, Frederick W., Frock, Richard L.
Gepubliceerd in Proc Natl Acad Sci U S A (2016)

Cell-Extrinsic Defective Lymphocyte Development in Lmna(-/-) Mice

door Hale, J. Scott, Frock, Richard L., Mamman, Sara A., Fink, Pamela J., Kennedy, Brian K.
Gepubliceerd in 2010

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases

door Frock, Richard L., Hu, Jiazhi, Meyers, Robin M., Ho, Yu-Jui, Kii, Erina, Alt, Frederick W.
Gepubliceerd in Nat Biotechnol (2014)

Detecting DNA Double-Stranded Breaks in Mammalian Genomes by Linear Amplification-mediated High-Throughput Genome-wide Translocation Sequencing (LAM-HTGTS)

door Hu, Jiazhi, Meyers, Robin M., Dong, Junchao, Panchakshari, Rohit A., Alt, Frederick W., Frock, Richard L.
Gepubliceerd in Nat Protoc (2016)

Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development

door Zhao, Lijuan, Frock, Richard L., Du, Zhou, Hu, Jiazhi, Chen, Liang, Krangel, Michael S., Alt, Frederick W.
Gepubliceerd in J Exp Med (2016)

Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation

door Frock, Richard L., Kudlow, Brian A., Evans, Angela M., Jameson, Samantha A., Hauschka, Stephen D., Kennedy, Brian K.
Gepubliceerd in 2006

Precise and broad scope genome editing based on high-specificity Cas9 nickases

door Wang, Qian, Liu, Jin, Janssen, Josephine M, Le Bouteiller, Marie, Frock, Richard L, Gonçalves, Manuel A F V
Gepubliceerd in Nucleic Acids Res (2021)

A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation

door Johnson, Brett R., Nitta, Ryan T., Frock, Richard L., Mounkes, Leslie, Barbie, David A., Stewart, Colin L., Harlow, Ed, Kennedy, Brian K.
Gepubliceerd in 2004

Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes

door Hu, Jiazhi, Zhang, Yu, Zhao, Lijuan, Frock, Richard L., Du, Zhou, Meyers, Robin M., Meng, Fei-long, Schatz, David G., Alt, Frederick W.
Gepubliceerd in Cell (2015)

Mechanism of tandem duplication formation in BRCA1 mutant cells

door Willis, Nicholas A., Frock, Richard L., Menghi, Francesca, Duffey, Erin E., Panday, Arvind, Camacho, Virginia, Hasty, E. Paul, Liu, Edison T., Alt, Frederick W., Scully, Ralph
Gepubliceerd in Nature (2017)

Expanding the editable genome and CRISPR–Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking

door Chen, Xiaoyu, Tasca, Francesca, Wang, Qian, Liu, Jin, Janssen, Josephine M, Brescia, Marcella D, Bellin, Milena, Szuhai, Karoly, Kenrick, Josefin, Frock, Richard L, Gonçalves, Manuel A F V
Gepubliceerd in Nucleic Acids Res (2020)

Ku70 suppresses alternative end joining in G1-arrested progenitor B cells

door Liang, Zhuoyi, Kumar, Vipul, Le Bouteiller, Marie, Zurita, Jeffrey, Kenrick, Josefin, Lin, Sherry G., Lou, Jiangman, Hu, Jianqiao, Ye, Adam Yongxin, Boboila, Cristian, Alt, Frederick W., Frock, Richard L.
Gepubliceerd in Proc Natl Acad Sci U S A (2021)

Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR–Cas9 genome editing

door Paulsen, Bruna S., Mandal, Pankaj K., Frock, Richard L., Boyraz, Baris, Yadav, Rachita, Upadhyayula, Srigokul, Gutierrez-Martinez, Paula, Ebina, Wataru, Fasth, Anders, Kirchhausen, Tomas, Talkowski, Michael E., Agarwal, Suneet, Alt, Frederick W., Rossi, Derrick J.
Gepubliceerd in Nat Biomed Eng (2017)

Correction: Cardiomyocyte-Specific Expression of Lamin A Improves Cardiac Function in Lmna (−/−) Mice

door Frock, Richard L., Chen, Steven C., Dai, Dao-Fu, Frett, Ellie, Lau, Carmen, Brown, Christina, Pak, Diana N., Wang, Yuexia, Muchir, Antoine, Worman, Howard J., Santana, Luis F., Ladiges, Warren C., Rabinovitch, Peter S., Kennedy, Brian K.
Gepubliceerd in 2012

Cardiomyocyte-Specific Expression of Lamin A Improves Cardiac Function in Lmna (−/−) Mice

door Frock, Richard L., Chen, Steven C., Da, Dao-Fu, Frett, Ellie, Lau, Carmen, Brown, Christina, Pak, Diana N., Wang, Yuexia, Muchir, Antoine, Worman, Howard J., Santana, Luis F., Ladiges, Warren C., Rabinovitch, Peter S., Kennedy, Brian K.
Gepubliceerd in 2012

Genome-Wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells

door Chiarle, Roberto, Zhang, Yu, Frock, Richard L., Lewis, Susanna M., Molinie, Benoit, Ho, Yu-Jui, Myers, Darienne R., Choi, Vivian W., Compagno, Mara, Malkin, Daniel J., Neuberg, Donna, Monti, Stefano, Giallourakis, Cosmas C., Gostissa, Monica, Alt, Frederick W.
Gepubliceerd in 2011

Parp3 promotes long-range end joining in murine cells

door Layer, Jacob V., Cleary, J. Patrick, Brown, Alexander J., Stevenson, Kristen E., Morrow, Sara N., Van Scoyk, Alexandria, Blasco, Rafael B., Karaca, Elif, Meng, Fei-Long, Frock, Richard L., Tivey, Trevor, Kim, Sunhee, Fuchs, Hailey, Chiarle, Roberto, Alt, Frederick W., Roberts, Steven A., Weinstock, David M., Day, Tovah A.
Gepubliceerd in Proc Natl Acad Sci U S A (2018)