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Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
Although great progress has been made in the characterization of off-target effects of engineered nucleases, sensitive and unbiased genome-wide methods for the detection of off-target cleavage events and potential collateral damage are still lacking. Here we describe a linear amplification–mediated...
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| Publicado no: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320661/ https://ncbi.nlm.nih.gov/pubmed/25503383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3101 |
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