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DNA double-strand breaks as drivers of neural genomic change, function, and disease

Early work from about two decades ago implicated DNA double-strand break (DSB) formation and repair in neuronal development. Findings emerging from recent studies of DSBs in proliferating neural progenitors and in mature, non-dividing neurons suggest important roles of DSBs in brain physiology, agin...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Alt, Frederick W., Schwer, Bjoern
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340756/
https://ncbi.nlm.nih.gov/pubmed/30195640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.08.019
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