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Editing the Genome Without Double-Stranded DNA Breaks
Genome editing methods have commonly relied on the initial introduction of double-stranded DNA breaks (DSBs), resulting in stochastic insertions, deletions, and translocations at the target genomic locus. To achieve gene correction, these methods typically require the introduction of exogenous DNA r...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5891729/ https://ncbi.nlm.nih.gov/pubmed/28957631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00710 |
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