Nalaganje...

Editing the Genome Without Double-Stranded DNA Breaks

Genome editing methods have commonly relied on the initial introduction of double-stranded DNA breaks (DSBs), resulting in stochastic insertions, deletions, and translocations at the target genomic locus. To achieve gene correction, these methods typically require the introduction of exogenous DNA r...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Chem Biol
Main Authors: Komor, Alexis C., Badran, Ahmed H., Liu, David R.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891729/
https://ncbi.nlm.nih.gov/pubmed/28957631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00710
Oznake: Označite
Brez oznak, prvi označite!