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Zinc Finger Nuclease Induced DNA Double Stranded Breaks and Rearrangements in MLL

Radiation treatment or chemotherapy has been linked with a higher risk of secondary cancers such as therapy related Acute Myeloid Leukemia (tAML). Several of these cancers have been shown to be correlated to the introduction of double stranded breaks (DSB) and rearrangements within the Mixed Lineage...

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Detalhes bibliográficos
Main Authors: Do, To Uyen, Ho, Bay, Shih, Shyh-Jen, Vaughan, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578303/
https://ncbi.nlm.nih.gov/pubmed/23291497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2012.12.006
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