Transparency Is the Key to Quality

Por Fosang, Amanda J., Colbran, Roger J.
Publicado no J Biol Chem (2015)

The 45 kDa collagen-binding fragment of fibronectin induces matrix metalloproteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases.

Por Stanton, Heather, Ung, Linh, Fosang, Amanda J
Publicado em 2002

The Accumulation of Intracellular ITEGE and DIPEN Neoepitopes in Bovine Articular Chondrocytes Is Mediated by CD44 Internalization of Hyaluronan

Por Flory, Jennifer J. Embry, Fosang, Amanda J., Knudson, Warren
Publicado em 2006

Internalization of Aggrecan G1 Domain Neoepitope ITEGE in Chondrocytes Requires CD44

Por Ariyoshi, Wataru, Knudson, Cheryl B., Luo, Na, Fosang, Amanda J., Knudson, Warren
Publicado em 2010

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity

Por Karsdal, Morten A, Madsen, Suzi H, Christiansen, Claus, Henriksen, Kim, Fosang, Amanda J, Sondergaard, Bodil C
Publicado em 2008

Evidence for lysosomal exocytosis and release of aggrecan-degrading hydrolases from hypertrophic chondrocytes, in vitro and in vivo

Por Bastow, Edward R., Last, Karena, Golub, Sue, Stow, Jennifer L., Stanley, Amanda C., Fosang, Amanda J.
Publicado em 2012

Mast Cell-restricted, Tetramer-forming Tryptases Induce Aggrecanolysis in Articular Cartilage by Activating Matrix Metalloproteinase-3 and -13 Zymogens()

Por Magarinos, Natalia J., Bryant, Katherine J., Fosang, Amanda J., Adachi, Roberto, Stevens, Richard L., McNeil, H. Patrick
Publicado em 2013

ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5

Por Rogerson, Fraser M., Last, Karena, Golub, Suzanne B., Gauci, Stephanie J., Stanton, Heather, Bell, Katrina M., Fosang, Amanda J.
Publicado no Int J Mol Sci (2019)

Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair

Por Little, Christopher B., Meeker, Clare T., Golub, Suzanne B., Lawlor, Kate E., Farmer, Pamela J., Smith, Susan M., Fosang, Amanda J.
Publicado em 2007

Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair

Por Little, Christopher B., Meeker, Clare T., Golub, Suzanne B., Lawlor, Kate E., Farmer, Pamela J., Smith, Susan M., Fosang, Amanda J.
Publicado em 2008

Cortisol enhances structural maturation of the hypoplastic fetal lung in sheep

Por Boland, Rochelle, Joyce, Belinda J, Wallace, Megan J, Stanton, Heather, Fosang, Amanda J, Pierce, Richard A, Harding, Richard, Hooper, Stuart B
Publicado em 2004

Matrix Metalloproteinases Are Not Essential for Aggrecan Turnover during Normal Skeletal Growth and Development

Por Little, Christopher B., Meeker, Clare T., Hembry, Rosalind M., Sims, Natalie A., Lawlor, Kate E., Golub, Sue B., Last, Karena, Fosang, Amanda J.
Publicado em 2005

An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2

Por Miller, Rachel E., Ishihara, Shingo, Tran, Phuong B., Golub, Suzanne B., Last, Karena, Miller, Richard J., Fosang, Amanda J., Malfait, Anne-Marie
Publicado no JCI Insight (2018)

Glucocorticoids influence versican and chondroitin sulphate proteoglycan levels in the fetal sheep lung

Por McDougall, Annie R. A., Fosang, Amanda J., Faggian, Jessica, Wallace, Megan J., Crossley, Kelly J., Cole, Timothy J., Hooper, Stuart B.
Publicado no Respir Res (2018)

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

Por Stickens, Dominique, Behonick, Danielle J., Ortega, Nathalie, Heyer, Babette, Hartenstein, Bettina, Yu, Ying, Fosang, Amanda J., Schorpp-Kistner, Marina, Angel, Peter, Werb, Zena
Publicado em 2004

A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers

Por Kosasih, Hansen J., Last, Karena, Rogerson, Fraser M., Golub, Suzanne B., Gauci, Stephanie J., Russo, Vincenzo C., Stanton, Heather, Wilson, Richard, Lamande, Shireen R., Holden, Paul, Fosang, Amanda J.
Publicado no J Biol Chem (2016)