Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity

INTRODUCTION: Physiological and pathophysiological cartilage turnover may coexist in articular cartilage. The distinct enzymatic processes leading to irreversible cartilage damage, compared with those needed for continuous self-repair and regeneration, remain to be identified. We investigated the ca...

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Main Authors: Karsdal, Morten A, Madsen, Suzi H, Christiansen, Claus, Henriksen, Kim, Fosang, Amanda J, Sondergaard, Bodil C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483454/
https://ncbi.nlm.nih.gov/pubmed/18513402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2434
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